
She won two Best Actress Academy Awards for playing "southern belles": Scarlett O'Hara in Gone with the Wind (1939) and Blanche DuBois in A Streetcar Named Desire (1951), a role she had also played on stage in London's West End.
She was a prolific stage performer, frequently in collaboration with her husband, Laurence Olivier, who directed her in several of her roles. During her 30-year stage career, she played parts that ranged from the heroines of Noël Coward and George Bernard Shaw comedies to classic Shakespearean characters such as Ophelia, Cleopatra, Juliet and Lady Macbeth.
Leigh sought the role of Blanche DuBois in the West End stage production of Tennessee Williams's A Streetcar Named Desire, and was cast after Williams and the play's producer Irene Mayer Selznick saw her in the The School for Scandal and Antigone, and Olivier was contracted to direct. Containing a rape scene and references to promiscuity and homosexuality, the play was destined to be controversial, and the media discussion about its suitability added to Leigh's anxiety, but she believed strongly in the importance of the work.
When the West End production of Streetcar opened in October 1949, J. B. Priestley denounced the play and Leigh's performance, and the critic Kenneth Tynan commented that Leigh was badly miscast because British actors were "too well-bred to emote effectively on stage". Olivier and Leigh were chagrined that part of the commercial success of the play lay in audience members attending to see what they believed would be a salacious and sensationalist story, rather than the Greek tragedy that they envisioned, but the play also had strong supporters,among them Noël Coward who described Leigh as "magnificent."
After 326 performances, Leigh finished her run. However, she was soon engaged for the film version. Her irreverent and often bawdy sense of humour allowed her to establish a rapport with her co-star Marlon Brando, but she had difficulty with the director Elia Kazan, who did not hold her in high regard as an actress. He later commented that "she had a small talent", but as work progressed, he became "full of admiration" for "the greatest determination to excel of any actress I've known. She'd have crawled over broken glass if she thought it would help her performance." Leigh found the role gruelling and commented to the Los Angeles Times, "I had nine months in the theatre of Blanche DuBois. Now she's in command of me." Olivier accompanied her to Hollywood where he was to co-star in William Wyler's Carrie.
The film won glowing reviews for her, and she won a second Academy Award for Best Actress, a BAFTA Award and a New York Film Critics Circle Award for Best Actress. Tennessee Williams commented that Leigh brought to the role "everything that I intended, and much that I had never dreamed of", but in later years, Leigh would say that playing Blanche DuBois "tipped me over into madness."
Lauded for her beauty, Leigh felt that it sometimes prevented her from being taken seriously as an actress, but ill health proved to be her greatest obstacle. Affected by bipolar disorder for most of her adult life, she gained a reputation for being difficult to work with, and her career went through periods of decline. She was further weakened by recurrent bouts of chronic tuberculosis, with which she was first diagnosed in the mid-1940s. She and Olivier divorced in 1960, and Leigh worked sporadically in film and theatre until her death from tuberculosis, in 1967.